Reinhardt Research Group at University of Vermont

Researchers at work, check back soon!

Full Publication List available at Google Scholar

Role of Active Site Residues and Weak Noncovalent Interactions in Substrate Positioning in N, N-Dimethylformamidase

Reinhardt, C. R.; Kastner, D. W.; Kulik, H. J.; Biochemistry. 2025, In Press.

Fontimonas thermophila Alkane Monooxygenase (FtAlkB) Is an Alkyl Fluoride Dehalogenase

Hendricks, L.; Reinhardt, C. R.; Green, T.; Kuncyznski, L.; Roberts, A.; Miller, N.; Rafalin, N.; Kulik, H. J.; Groves, J. T.; Austin, R. N. J. Am. Chem. Soc. 2025, 147, 11, 9085–9090.

No Bridge Between Us: Two Distant Iron Ions
Comprise the Active Site of Alkane Monoxygenase (AlkB)

Reinhardt, C. R.; Lee, J.; Hendricks, L.; Green, T.; Kuncyznski, L.; Roberts, A.; Miller, N.;
Rafalin, N.; Kulik, H. J.; Pollock, C.; Austin, R.N. J. Am. Chem. Soc. 2025, 147, 3, 2432–2443.

Nuclear Quantum Effects in Quantum
Mechanical/Molecular Mechanical Free Energy Simulations of Ribonucleotide Reductase

Chow, M.; Reinhardt, C.R.; Hammes-Schiffer, S. J. Am. Chem. Soc. 2024, 146, 48, 33258–33264.

Computational Screening of Putative Transition Metal Complexes as Guests in a Ga₄L₆ Nanocage

Reinhardt, C.R.; Manetsch, M.T.; Li, W.L.; Román-Leshkov, Y.; Head-Gordon, T.; Kulik, H. J. Inorg. Chem. 2024, 63, 14609–14622.

Switching the Proton-Coupled Electron Transfer Mechanism for Non-Canonical Tyrosine Residues in a de novo Protein

Nilsen-Moe, A.; Reinhardt, C.R.; Huang, P.; Agarwala, H.; Lopes, R.; Lasagna, M.; Glover,
S.; Hammes-Schiffer, S.; Tommos, C.; Hammarström, L. Chem. Sci. 2024, 15, 3957-3970.

Enabling Analysis and Extraction of Metal-Containing Sites from the Protein Data Bank with molSimplify

Edholm, F.; Nandy, A.; Reinhardt, C.R.; Kastner, D.W.; Kulik, H.J. J. Comput. Chem. 2024, 45, 352.

Direct Proton-Coupled Electron Transfer between Interfacial Tyrosines in Ribonucleotide Reductase

Zhong, J.; Reinhardt, C.R.; Hammes-Schiffer, S., J. Am. Chem. Soc. 2023, 145, 4784-4790.

Student-led workshop strengthens perceived discussion skills and community in an interdisciplinary graduate program

Shipps, C.; Thrush, K.L., Reinhardt, C.R.; Siwiecki, S.A.; Claydon, J.L.; Noble, D.B.; O’Hern, C.S. FASEB BioAdvances 2022; 00: 1-12.

Kinetic Model for Reversible Radical Transfer in Ribonucleotide Reductase

Reinhardt, C.R.*; Konstantinovsky, D.*; Soudackov, A.V.; Hammes-Schiffer, S. Proc. Natl. Acad. Sci. USA 2022, 119, e2202022119.